Backpacking in South America: 10 Incredible Routes from 1-6 weeks

Discover 10 Incredible Routes to go backpacking in South America

South America is a huge territory, and it can be intimidating to choose where to start. In order to help you to decide on a perfect South America backpacking route that is the best for you, I put together these 10-routes from 1-week to 6-week itineraries. 

I got you! You are dreaming about go backpacking in South America and are not sure where to start? I am born and raised in Brazil, and South America is pretty huge…and amazing!

Whether you have some bucket list destinations that are unmissable, such as Hike Patagonia, explore Machu Picchu, or soak in the sun in Copacabana Beach in Rio de Janeiro, here you can find the perfect itinerary to go Backpacking in South America. 

Why this is the most complete guide for backpacks in South America?

Well, amigos, this guide is a collaboration between some professional travel bloggers from all over the world, who have put these routes together, combined with my experience as I was born and raised in South America. With so much expertise, here you can find the best route for you. All you need is to invest in the Best Backpack for Backpacking and decide on your route. 

You will fall in love with the continent with an incredible variety of things to do, and places to visit from pristine beaches on the coast to lush forests, historical towns, ancient ruins, and towering mountains. In South America, you can also find some of the best hikes on the Planet. 

Even better, it is very affordable and safe to travel around South America, doesn’t matter if your adventure includes hitchhiking or fly around your amazing South America backpack route. 

Enjoy it and safe travels!

Backpacking in South America

Backpacking is a form of low-cost, independent travel, which often includes staying in inexpensive lodgings and carrying all necessary possessions in a backpack. Once seen as a marginal form of travel undertaken only through necessity, it has since become a mainstream form of tourism



Finding the best South American backpacking route for you depends on a couple of things, and a good start is to ask yourself these 3 mains questions:

  • How much time you have: 1-week, 2-weeks, 3-weeks, 1 month?
  • What is your budget: Are you planning to travel on a budget or you are more of a flashpacker?
  • What are your main interested: Are you looking to visit historic cities and enjoy the local cuisine? Or maybe you want to go trekking? Maybe you are looking for more adventures such as surfing, scuba diving, visit jungles…

South America is without a doubt one of the most diverse continents on the Planet. Here you can find the largest forest in the world, the Amazon. It is home to the world’s second-highest mountain ranges in the Anes. You can also find world-class surf beaches. Plus you can explore glaciers, deserts and very unique wildlife.

South America attracts and older and more experienced backpacker visitors than Southeast Asia, and here you have plenty of options to get off-the-beaten-path, and it is definitely one of the ultimate backpacking destinations. 

Backpacking in South America Patagonia


BrazilSão Paulo | Paraty | Rio de Janeiro1- WeekHave a taste of Brazil with this 1-week route, great for fun, culture, and outdoor lovers. Enjoy the amazing local cuisine and art in Paraty. Visit the main spots of the 2 major cities in Brazil.
BrazilSão Paulo | Curitiba | Iguaçu Falls | Florianopolis2- WeeksCultural visit in São Paulo with many museums to explore. Curitiba is a very unique and modern city, and follow to one of the Wonders of the World, the Iguaçu Falls. Florianopolis is a paradise for outdoor lovers and surfer.
Argentina & ChileBuenos Aires | Puerto Madryn | Ushuaia | Torres Del Paine | Perito Moreno | Bariloche | Santiago | Valparaiso | Mendoza | Salta | Iguaçu Falls3 - 6 WeeksWith this itinerary, you are able to explore the big highlights of both countries. With lots of outdoor activities and wildlife along the way. Visit wineries in Argentina, go hiking, and whale watching on this route.
Bolivia & ChileLa Paz | Uyuni | San Pedro de Atacama | 1 - WeekYou can do this route in only 1-week on an off-road adventure. This is a short length route, but full of adventure along the way.
Colombia & PeruCartagena | Medellin | Bogota | Lima | Arequipa | Cusco | Machu Picchu3 - 4 - WeeksVisit some of the main cities in both countries. Enjoy the phenomenal cuisine and learn more about the ancient history of the Incas. Visit the incredible Colca Canyon and the ancient town of Machu Picchu
EcuadorQuito | Cotopaxi Volcano | Quilotoa Crater Lake | Mitad del Mundo| Cuenca | 9 - 14 DaysExplore Quito and enjoy some day trips to Cotopaxi Volcano & Quilotoa Crater. For outdoor lovers, go hike in Las Cajas National Park.
Patagonia - Chile & ArgentinaStarts in Puerto Montt | Finish in Puerto Natales2 - 3 WeeksThis off-the-beaten-path route is about 1,243 miles. It is a great route for adventure travelers and for hitchhiking. Plenty of outdoor activities such as hiking, kayaking, and mountain-bike
PeruCuzco | Machu Picchu | Arequipa | Chivay | Valle del Colca | Puno | Lake Titicaca2 - WeeksThis amazing route is the best option to visit the main highlights in Peru. Great for adventure travelers with plenty of outdoor activities. Visit the ancient town of Machu Picchu and go hike the Montaña Machu Picchu and Huayna Picchu. Go hike the Colca Canyon and visit the incredible floating islands at Lake Titicaca.
Colombia & ArgentinaBogota | Medellin | Lima | Buenos Aires | Patagonia2 - 3 WeeksThis route takes you to the best cities in South America. With plenty of cultural options and also, to enjoy the incredible local cuisine.
Chile & ArgentinaSan Pedro de Atacama | Atacama desert | Valparaiso | Santiago | Mendoza | Buenos Aires4 - 6 WeeksIf you have more time to backpack South America this is the perfect route for you. Great for adventure travelers and hitchhiking/ camping. Travel slower and on a budget, seeing the most amazing spots of each country.


HOW TO GET TO SOUTH AMERICA: There are several airlines for you to choose from, it depends on your departure and final destinations, I recommend flying to a large city. In order to find the best prices, you can browse and compare the best deals with Expedia or Skyscanner

BUDGET: The good news is that backpacking in South America is very affordable, especially if you are traveling from other parts of the world, such as the U.S. or Europe when the exchange rate is really good. Planning an average budget of $50 to $100 USD per day/ person is relatively easy.

TRANSPORTATION: When you choose to backpack in South America, it is important to know that it is generally easy to get around the continent. It is really inexpensive to travel by just or fly. Trains are relatively rare in South America. If you decide to rent a car, it is also a good option as you can find the major international rental car companies in the main airports. South America is also safe if you decide to hitchhike around.

GROUP & PRIVATE TOURS: Group or private tours are also great options, especially for some activities. A safe and great option I recommend is to book through Viator or Get Your Guide, as they have many options for tours and you can plan and book ahead.

ACCOMMODATIONS: You can find a large range of accommodations from a budget hostel or basic hotel to a large hotel chain. Make sure you book your accommodation from a reliable source, where you can also make cancelations within 24-hours. I recommend using because of the thousands of reliable options.

SAFETY: Backpacking in South America is safe, as long as you pre-plan your route. Have a plan on where you will stay, what transportation will you take, and places you want to visit. Also, leave your jewelry at home, and watch your electronics closely.

TRAVEL INSURANCE: Don’t travel to South America without Travel Insurance, as anything can go wrong. I use and recommend World Nomads, as they are the best option for travel insurance that fits any kind of adventure.

LANGUAGE: Don’t expect many people to speak English outside the major cities in South America. I recommend trying to learn some basic Spanish before your trip, or Portuguese if you are traveling to Brazil. It can be as easy as these 13 cools ways to learn Spanish without leaving home. If you don’t have the chance to learn the language, you can take with you a Spanish phrasebook or if you are going to Brazil take a Portuguese phrasebook. Or take a Translator device is also a good option. 

BACKPACK FOR BACKPACKING: Make sure you invest in a good quality backpack that is comfortable to carry around and you can fit all your belongings safely. 

WHEN TO VISIT SOUTH AMERICA: It really depends where you are going. The countries near the equator do not experience distinct seasons. As you go further south, the more seasonal the climate. Remember that the southern hemisphere seasons are reversed, with summer roughly from November to February, and winter from June to August. The high season for all countries in South America is from December-February. Check the weather for the destination you are going to. 

Backpacking in South America Peru



One of the best destinations in South America for backpackers is Brazil. Besides being the largest country in South America, it is ironically a great destination for a 1-week only.

It happens because of the large variety of options of places to visit within São Paulo and Rio de Janeiro states – and they are only 6-hours driving apart. If you are planning a trip to Brazil, this is a great route for you to experience the fun, culture, and beauty of this vast country. 


Santos is great destination when you backpacking in Brazil

Start this South America backpack route in the largest city in Brazil, São Paulo. You have the option to hire a private guide or to visit by yourself.

Visit the Park Ibirapuera, an urban oasis in the middle of the city. Visit the Vila Mariana is known as the bohemian, culture, and art neighborhood.

On the second day, visit the Cathedral da Sé in the city center, the Municipal Theater which is one of the most important landmarks in São Paulo, and have lunch at the Mercado Municipal. You can rent a bike and ride down the Avenida Paulista, the city’s most important road. If you have more time, you can take amazing day trips from São Paulo. 


Backpacking in South America Paraty
Paraty, Rio de Janeiro – Brazil

Head to Paraty in Rio de Janeiro state (5-hour driving distance). You can take a bus or rent a car. Here you can enjoy one of the most spectacular settings of preserved colonial center, the incredible ocean, surrounded by mountains.

Take a boat tour for the day and go on an island hop. You can do kayaking, the city center sightseeing tour and also, take a Jungle-jeep tour and visit the many incredible waterfalls.  


Sugar loaf interesting facts
Cable car to Sugar Loaf, Rio de Janeiro – Brazil

From Paraty, go to Rio. You can take a bus or rent a car and drive for less than 4-hours. In days you can have the taste of this marvelous city, and to get to learn some of the Rio amazing fun facts. If you take a private tour, you get to visit the main attractions in the city in as short as one day and use the second day to soak by the Copacabana Beach and enjoy some coconut water, while watching the incredible views of your surroundings. 

2) BRAZIL ROUTE: 2-Weeks

If you have weeks to spend backpacking in Brazil, this is the best route for you. The majority of the international flights arrive at the airport in São Paulo. If this is your case, start your trip to São Paulo. If you fly to Rio, you can start your 2-week in Brazil route spending the first few days before you continue your trip. 


Brazil -Travel Guide need to know
The train station of Luz, in the city of São Paulo

You can follow the same itinerary for São Paulo suggested above, or you can hire a private driver to explore more this large and amazing city. São Paulo has also many museums to visit, and if you have more time, the best ones are: Pinacoteca, MASP (Museu de Arte de São Paulo), Museu do Ipiranga, Museu de Art Moderna (MAM).


From São Paulo, head to the south of Brazil to another amazing large city, Curitiba. It is less than 6-hour driving/ bus or you can take a 1-hour flight. Here you can explore one of the greenest cities in the world. You can hire a private driver or explore by yourself. Visit the unique Wire Opera House, sample some international food and drinks in the Italian Woods neighborhood, take a walking tour of the historic district and enjoy other great activities, such as the scenic train ride Curitiba-Paranaguá.


Backpacking South America Iguaçu Falls
Iguaçu Falls

Head next to Iguaçu Falls, to see one of the Seven Natural Wonders of the World. You can take a short and cheap flight from Curitiba, or take a bus/ car for an 8-hour drive. You can visit the waterfalls in different ways, like by walking or boat tours. While in the area, you can walk along two bridges, as Iguaçu City is located at the triple border of Brazil, Argentina, and Paraguay. You need to buy your ticket in advance – check here for the tickets


Backpacking South America Santa Catarina
Florianópolis, Santa Catarina – Brazil

From Curitiba, head to Florianopolis for some relaxation on this magical island. It is less than a 5-hour drive/ car or you can take an affordable domestic flight. Floripa, as the locals call it, is filled with white-sand beaches, diverse hiking trails, and lush rainforests. The center of the island has a hippie vibe, with a trendy area and rustic restaurants, perfect for backpackers. 

3) ARGENTINA & CHILE ROUTE: 3 to 6 Weeks

If you have 3 weeks to backpack in South America this is a great route. But if you have more time to explore slower each location, it is even better. Traveling to the most southern tip of South America is one of the best trips you can make! Spend three to six weeks exploring the most beautiful destinations in Argentina and Chile with this bucket list Argentina-Chile travel itinerary, covering all the big highlights of both countries.


Start your trip in Buenos Aires, the capital of Argentina, and of the tango. The city has many landmarks, museums, restaurants, and different neighborhoods to keep you entertained for weeks. Try to keep your stay limited to a few days, especially as you’ll be coming back at the end of your trip.


Backpacking South America

CONTRIBUTED BY: Maartje from The Orange Backpack

Head to Puerto Madryn and the Peninsula Valdes by bus. This is one of the most beautiful nature reserves in Argentina, known for its whale watching opportunities June-December. There are penguins, elephant seals, and other wildlife as well – Check for tickets here


Take the bus further south to the most southern city in the world: Ushuaia. It’s a great place for skiing, exploring small glaciers, and hiking in the Tierra del Fuego national park.


Your next stop should be Torres del Paine, one of the most stunning reserves for multiday hikes. You’ll see wildlife, camp in beautiful places, and enjoy some stunning glaciers.


Take the bus to the biggest glaciers outside the poles next: the Perito Moreno. There is not much else to do in the area, so don’t stay too long and just focus on a trip to the glacier.


Backpacking in South America

Head to Bariloche for its stunning lake district next, cross the border with Chile and enjoy the lakes from the Chilean side as well before heading up north. Both are great places for hiking.


Backpacking South America Santiago Chile

Chile’s capital Santiago is your next stop, but make sure to include a day trip to graffiti capital Valparaiso as well.


Cross the border once more and visit Mendoza in the wine region of Argentina to make a wine tour and visit some wineries for tastings.


Salta is your next stop. This charming small town has plenty of things to do, so take your time to visit the salt flats, Purmamarca mountains, the vineyards, and canyons.


If you have enough time, you could add the Iguazu waterfalls to this itinerary, but it takes a while to reach them. Otherwise, head back to Buenos Aires to fly home.


Only have a week to backpack South America, but want to squeeze in an off-road adventure? Bring your energy, because this grueling itinerary takes you through some of the most surreal landscapes on the planet. 


Backpacking South America

CONTRIBUTED BY: Nate from Travel Lemming

Start your journey in La Paz, Bolivia’s capital and city in the clouds. Sitting at 3,640 meters above sea level, La Paz is the highest capital city in the world. If you are coming from a lower elevation, be sure to take it easy on your first day to give your body time to acclimate. A great relaxing activity is to ride the public transit gondolas that whisk local commuters around La Paz. One day 2, explore the city. In the evening grab the 9-hour overnight bus to the desert town of Uyuni.


Backpacking in South America

There isn’t much to see in Uyuni apart from a “train graveyard,” but you won’t be staying here overnight anyway. Instead, pre-book a three-day 4WD tour through the Uyuni Salt Flats, one of the most popular activities in Bolivia.

The Uyuni Salt Flats route is plied by dozens of jeeps every day and is one of the most quintessential backpacker experiences in South America. You and your traveling companions will spend your days exploring otherworldly landscapes, including the famous Uyuni Salt flats, where endless salt flats let photographers play with perspective. 


Backpacking in South America

You’ll end your road trip by crossing the border in Chile, where you can find lots of backpacker accommodation in San Pedro de Atacama for your final two nights. Owing to the lack of light pollution, this is one of the best places on the planet for stargazing. You can also explore the famous Valle de la Luna, where giant sand dunes appear like Martian landscapes. San Pedro has an airport with connections to Santiago, or you can continue your backpacker journey down the coast of Chile.


Another amazing route to backpack South America, and explore from the tropical Paradise in the Caribean to uncover one of the top destinations in South America, Peru, and the amazing cuisine to the ancient history of the Incas. You can do this route in 3 weeks and if you have more time to explore South America, extend your stay to 4-weeks. 


Backpacking in South America

CONTRIBUTED BY: Ben from Ticket 4 Two Please

Start your backpacking adventure in Colombia and the Northern beach town of Cartagena. Admire the colonial architecture in the Walled City (Old City) before taking a few days to explore the islands of Tierra Bomba – a tropical paradise in the Caribbean. 


A 13-hour bus journey south through rural Colombia brings you to the famous city of Medellin. Once home to the infamous Narcoterrorist Pablo Escobar, Medellin was once considered the most dangerous city in the world. Discover the city’s tumultuous past on a Comuna 13 tour and conquer the 740 step ascent of El Peñón de Guatapé.


Time to explore the capital city of Colombia. An 8-hour bus journey from Medellin and is your last destination in Colombia. Wander around the Candelaria district, unearthing commissioned street art pieces on back-alley walls.


Continue your backpack in the South America route, leaving Colombia behind, for now, a 3-hour flight from Bogota brings you to your first destination in Peru – Lima. The capital city is a great place to be introduced to Peruvian cuisine and the famous ceviche – a dish of raw fish cured in citrus juices. Try washing it down with a pisco sour, the national drink of Peru.


Backpacking in South America

Your nest destination is Arequipa, accessible from Lima via overnight bus or 90-minute flight, is a great base to explore one of the natural wonders of Peru. Take a day trip to the breathtaking Colca Canyon, the second deepest canyon in the World.

 DAYS 17-19: CUSCO

Your final destination on your whistle-stop 3 to 4-week backpacking tour around South America is Cusco. Explore the heart of Sacred Valley at the Moray ruins and Maras Salt mines, before heading off to the highlight of any South America excursion: Machu Picchu – Check train tickets here.


Backpacking in South America
Machu Picchu – Peru

Discover the history of the famous Inca ruins on a day trip from Ollantaytambo, or via the 3 day Inca trek. Whichever way you choose to explore Machu Picchu, it is sure to provide a wonderful culmination to your trip!

6) ECUADOR ROUTE: 9-14 Days

Ecuador is one of the best and epic routes to Backpack in South America. With plenty of budget options and easy and cheap transportation between places. The ideal length of this Ecuador route is 9-14 days. You have several options of day trips from Quito, or you can always spend more time in each place if you have the ability to. For easy day trips from Quito, visit the Cotopaxi Volcano and the Quilotoa Crater Lake for excellent hiking, located 50 km and 170 km away from Quito, respectively.


Backpacking in South America Ecuador

CONTRIBUTED BY: Tegan and Alex from Why Not Walk

Start your trip in Quito, the country’s capital and a vibrant, fun city to explore. Don’t miss the views of the city from El Panecillo, the basilicas and historic architecture, and delicious coffee and treats at Dulceria Colonial. Be sure to take it easy your first few days if you have just arrived in Ecuador, as altitude sickness is common due to the very high elevation, and will definitely ruin your trip. Consider chewing coca leaves to counter the effects, and be sure to drink lots of water and save your hiking excursions after you have adjusted to the altitude change.

DAY 5: COTOPAXI VOLCANO (option of a day trip from Quito)

Cotopaxi National Park is home to a massive volcano. The hike begins at 4600 meters above sea level at the parking area, then goes up to the Refugio (refuge) at 4800 meters, then continuing on the glacier at 5000 meters- Check here for day tours from Quito.

DAY 6: QUILOTOA CRATER LAKE (option of a day trip from Quito)

Backpacking South America Laguna quilotoa

Quilotoa is a caldera lake (a collapsed volcano) known for its other-worldly turquoise waters and spectacular views. You can trek down to the bottom and back (only 560m round trip, but very steep) on a day trip, and the Quilotoa Loop (also called the Quilotoa Traverse) is a 3-day hike that completes a loop around the top of the Laguna.

Quilotoa is a caldera lake (a collapsed volcano) known for its other-worldly turquoise water and spectacular views. You can trek down the bottom and back (only 560m round trip, but very steep) on a day trip, and the Quilotoa Loop (also called Quilotoa Traverse) is a 3-day hike that completes a loop around the top of the Laguna.

DAYS 7: MITAD DEL MUNDO (option of a day trip from Quito) 

Another must-see day trip location from Quito is the Mitad del Mundo, to experience the iconic sensation of standing with “one foot in each hemisphere!” You can book a day tour, take a bus, or take an Uber round-trip.


Backpacking in South America

Lastly, if you have the time, add on a quick and inexpensive flight to Cuenca. The flight only takes an hour, and Cuenca has so much to offer – thought to be Ecuador’s most “European city”, with lovely colonial architecture, beautiful weather, and museums. For outdoors lovers, you absolutely must take advantage of the spectacular hiking in the Las Cajas National Park.

Lastly, if you have the time, add on a quick and inexpensive flight to Cuenca. The flight only takes 1-hour, and Cuenca has so much to offer. Thought to be Ecuador’s most European city, with lovely colonial architecture, beautiful weather, and museums. For outdoor lovers, you absolutely must take advantage of the spectacular hiking in the Las Cajas National Park.


Traveling across Patagonia is an amazing backpacking experience. The suggested route starts in Puerto Montt and finishes in Puerto Natales.

The total distance of the route is about 1243 miles (2000 km) and takes between 2 to 3 weeks to complete, depending on how many stops you want to make. 

This backpacking route in South America includes off-the-beaten-path places and famous landmarks in two countries, Chile and Argentina.

CONTRIBUTED BY: Alya from Stringy Nomads

Hitchhiking is the most adventurous way of traveling through the region. Patagonia is one of the best places for hitchhiking; it’s safe, there are no dangerous wild animals, locals are very friendly and helpful. If hitchhiking is not your cup of tea you can explore the region by car or use local buses to commute between the towns and to cover long distances.

Cheap accommodation like camping and hostels is in abundance in the region which means traveling here can be done on a tight budget.

The big part of the route, 1200 km is on the Carretera Austral in Chile, a spectacular area with many outdoor activities. The scenery along the Carretera is fantastic; lush green forest, turquoise color lakes, mountain rivers, beautiful waterfalls, and picturesque mountains. The area has many incredible one-day and multi-day hikes, mountain-biking trails, and great spots for rafting and kayaking.


South America backpack route

The Argentinian part of the route includes El Chalten, the hiking capital of the country, and Perito Moreno Glacier, the most impressive natural attraction in this part of the world. Both places offer some incredible adventure experiences like hiking, rock climbing, glacier hiking, and kayaking. 

The route ends in Puerto Natales, a small town that is used as a gateway to the famous Torres del Paine National Park. The park is well-known as one of the best places for hiking in the region.

There are two challenging long-distance treks and many easy day-hikes. 

8) PERU ROUTE: 2-Weeks

Peru is a bucket list destination Backpack in South America for any backpacker lover. This is because of the variety of things to do and see while doing this route. With plenty of Inca historical sites to visit, the phenomenal local cuisine, to the Best Hikes in Peru, making it a paradise for Adventure Travelers –

Plus, travel in Peru is very cheap. Ideally, this route takes 2-weeks, but if you have less time, you can always skip some attractions and still explore Peru in less time. The best transportation options to travel around Peru are buses for long-distance, small group tour vans, and hiring a private driver to take you to sites around the Cusco region, as the prices are very affordable. 


Start this incredible South America backpack route in Cuzco, the archaeological capital of the Americas. Plan to spend a few days in Cusco, acclimatizing to the altitude (11,152 ft.). Make sure to visit the Cathedral in the main square and explore the busy city local market and the incredible local cuisine. 


Take a day trip from Cusco going on small group tours. Explore the fascinating Sacred Valley. Visit the ancient site of Pisac, the incredible Salinas de Maras, the sacred valley of  Urubamba, and the ancient Inca temple and fortress of Ollantaytambo.


You can go on a private tour or take the train from Cusco to Aguas Calientes. The next morning get up early and take the bus from Aguas Calientes to Machu Picchu and spend the day exploring the ancient city. You have the choice to climb the Montaña Machu Picchu and Huayna Picchu – you need to buy the ticket in advance. 


Take the night bus from Cusco to Arequipa (a 7-hour trip). Explore the legendary White City of Arequipa. Walk the Historic Center, visit the awe-inspiring museums. Don’t miss the Cathedral Basilica in the man square and the Santa Catalina Monastery. Visit the Yanahuara viewpoint for some good views and photos of the volcano El Misti.


This section of the trip is better done by a small group tour – check the options here. Visit one of the deepest Canyons in the world. Stop at Cruz del Cóndor for some of the most beautiful views of the canyon and to watch the flying of the condors. During this stunning driving, you will stop and appreciate farming terraces, ti vicunas, alpacas, llama. Visit eh Tocra lake to see the flamencos and some amazing landscapes.


Backpacking in South America Peru

This section of the trip is better done by a small group tour – check options here. Visit one of the deepest Canyons in the world. Stop at Cruz del Cóndor for some of the most beautiful views of the canyon and to watch the flying of the condors. During this stunning driving, you will stop and appreciate farming terraces, ti vicunas, alpacas, llamas. Visit eh Tocra lake to see the flamencos and some amazing landscapes.

DAYS 13: PUNO & LAKE TITICACA (day trip from Puno)

Take a full-day tour lunch to lake Titicaca. Spend the day at the world’s highest lake, Lake Titicaca. Visit the fascinating floating islands of Uros and hear from the locals how reed islands are made. Enjoy the performance and the nicely done fresh fish lunch from the Quechua community. Hike around the island for the great views. Make your way back to Arequipa.


Take the train back from Puno to Cuzco. Perurail offers daily departures.


When deciding which route to take on your South America backpacking trip you may be spoiled for choice. One route that you may want to consider to be able to see some of South America’s best cities would see you starting in Colombia’s capital and heading down to the Southern cone.


Backpacking in South America Bogota Colombia

CONTRIBUTED BY: Daniel from Layer Culture

Flying into Bogota, Colombia from the US or Europe you can get quickly get acquainted with the La Candelaria neighborhood, (a great place to try the best Colombian Food from all regions) and to see some of the country’s best museums and architecture. 


travel by bus up to Medellin (10 hrs) to explore the city of the eternal spring and to try the infamous Banjea Paisa. In Medellin, you can enjoy places such as the El Poblado neighborhood and take a trip to a local coffee farm


From Medellin take a plane directly to Lima (3 hrs) and explore the architecture of the colonial buildings the Centro Historico. Then do some souvenir shopping in Miraflores and spend a couple of nights in Barranco, Lima’s bohemian neighborhood where you’ll try some of Peru’s finest ceviche


Backpacking in South America Argentina

From Lima, you can get a direct flight to Buenos Aires (4 hrs) or even take the bus (72 hrs). On arrival to Buenos Aires head over to San Telmo, the oldest neighborhood in the city and be sure to see the bustling Sunday market there.

DAYS 14-21: PATAGONIA (suggested week 2 itinerary)

From Buenos Aires, you can extend this itinerary and travel to any other country in Latin America or head down to Patagonia and visit Punta Tombo, which is one of the best spots in Argentina to see the penguins.    


For the adventurous backpacker, the hitchhiking / camping trip from Chile to Argentina is an unforgettable and rewarding experience. This backpack South American route begins after a tour of Bolivia’s famous Uyuni salt flats, with San Pedro de Atacama being the drop-off point, and ends at the Argentinian capital, Buenos Aries. The whole trip can take between 4 to 6 weeks, depending on the number of stop-offs and luck at hitching a ride.

Hitchhiking is safe and straightforward in Chile and Argentina, with many friendly truckers wanting some company or just happy to give a helping hand. What’s more, is that these countries are perfect for camping. Chile’s Route 5 highway runs close to beaches which are a great spot to camp, and the Atacama desert is considered one of the best places in the world to see stars at night. The Argentinian countryside has plenty of forests, lakes, and campsites to enjoy the remote and beautiful outdoors.

Learning basic Spanish beforehand would be a bonus on this trip while spending the long hours with hitchhiking rides. Traveling as a couple is recommended for some company during those long waits to be picked up!

CONTRIBUTED BY: Matt from No Hassle Travel


From San Pedro, hitchhike west to the coastal city of Antofagasta, where camping supplies can be bought at the mall. On the outskirts of town is the surreal sculpture Mano de Desierto (hand of the desert), which is worth visiting.


Next, hitch a ride south, through the Atacama desert and towards La Serena, known for its beautiful beaches and historic churches. There are many towns along the coast worth exploring and camping on the beaches, such as Caldera and Puerto Viejo.


Continue south towards the trendy city of Valparaiso, full of brightly colored houses and creative street art. The Capital city of Santiago is just 70 miles east of here, which is the last stop in Chile before crossing the border into Argentina.


After crossing the border is Mendoza, Argentina’s most important city for producing wine and famous for winery tours. The Hitchhiking route will head east across the beautiful Argentinian Countryside. Some excellent stop-off points are the nature city of San Luis and the small town of Merlot, that’s surrounded by a spectacular mountainous landscape. Follow the route north towards the city of Cordoba, Argentina’s second-largest city. Then onto Buenos Aries, which is the final stop of this epic South American route!


I never leave my home without travel insurance which is designed to help cover your expenses if something goes wrong on your trip. Things can go wrong, and you don’t want to get stuck paying tons of money if you get sick or have an accident without travel insurance. 

World Nomads Travel Insurance has been designed by travelers for travelers, to cover their trip essentials. Especially if you are like me, travel insurance is ideal for adventurous travelers.

Travel smarter and safer – You can do your quick quote below and find out how little you can pay for the essential benefit of Travel Insurance for your next trip!


Well amigos, by now you can see that Backpacking South America is a dream destination for any adventurer traveler as it offers a large variety of incredible things to do, see and explore. There is a route for any adventure traveler or any taste or personal interest to choose from. 

Backpacking to South America is also an inexpensive trip where you can make the most of your budget. Also, it is safe to backpack in South America, as long as you plan and prepare before your trip. 

To really experience and emerge on the local culture, try not to stay at chain hotels or eat at fancy touristy restaurants. I don’t even need to mention to NEVER eat at fast food. Support the local economy in any way possible as eating at local restaurants, and by hiring a local guide when possible. 

When visiting remote places and interacting with indigenous villages or small communities, always ask before taking photos. Always show them the respect they all deserve.

I hope you found this guide to the best South America backpacking routes valuable, and if you have any additional questions, please just leave me a comment below. 

South America is the place I was born and raised, and I am so proud to share my homeland with you. 

I hope you have the best time of your life and Safe Travels!

Backpacking in South America | Lake Titicaca – Peru


If you are going to travel to South America, pre-planning, research, and understanding what you are looking for will help make your travels far more successful and safe.

Here is some further information I think you might need to plan your  trip:

Backpacking in South America

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2 thoughts on “Backpacking in South America: 10 Incredible Routes from 1-6 weeks

  1. Josy A says:

    Squeeee what an incredible itinerary for soooo many an epic trips! I love hiking so I have wanted to hike to Montaña Machu Picchu and Huayna Picchu…but other than that, I would want to spend plenty of time in Patagonia hiking until my legs can’t walk any further. 🙂

  2. Emma says:

    I haven’t been to South America yet, but I’m really interesting in visiting soon. Some of my friends have been and have already recommended Peru, Colombia and Ecuador, but I loved finding out more about some of the other countries and getting some sample itineraries. It’s honestly a bit overwhelming to figure out where to go first so this is super helpful. And I love the outdoors and hiking so I’m really excited to give some of these places a go

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